Research Interests

• Theory of optimal experimental designs
  • Optimal designs for nonlinear regression models
  • Optimal designs for correlated observations
  • Optimal designs for random-effect models
  • Designs for spatial models
  • Mixture experiments
• Efficient designs in biology, industry and market research
  • Dose finding studies in toxicology
  • Optimal designs in PK\PD modeling
  • Market research
• Algorithms for computing optimal and efficient designs
  • Fedorov-Wynn algorithm
  • Titterington algorithm
  • Stochastic optimization
  • Construction of Latin hypercube designs
• Design and analysis of computer experiments
  • Space-filling designs
  • Sequential designs
  • Bayesian analysis
  • Local regression approach
• Other interests
  • Time series analysis
  • Signal processing
  • Image analysis
  • Nonparametric estimation
  • Philosophy